I appreciated it, being in Boston, from what it could have been. It could have been boos,” he said. “. By psychiatric research standards, the numbers were huge: 851 patients in the Effexor XR group, 748 in the SSRI group (Prozac, Paxil, and Luvox), and 446 in the placebo group. The doses of comparator SSRIs were robust enough to mirror what we actually use in clinical practice, and treatment duration was reasonable, between 6 and 8 weeks. There are a few minor quibbles, including the fact that there was no comparison with either Celexa or Zoloft, but overall the study was solid, and the higher remission rate with Effexor seems pretty convincing, if not absolutely compelling..
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